157°(315°F) Density. ; Moffat, A.C., Gas-liquid chromatographic retention indices of 1318 substances of toxicological interest on SE-30 or OV-1 stationary phase, J. Chemsrc provides Salicylic acid(CAS#:69-72-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Applications. 5 Chemical Vendors. Salicylic acid (from Latin salix, willow tree) is a lipophilic monohydroxybenzoic acid, a type of phenolic acid, and a beta hydroxy acid (BHA). N,N-bis(2-pyridin-2-yl-ethyl)-hydroxylamine (6965-67-9), (2E)-3-methoxy-2-methyl-2-propenoyl isocyanate, (E)-N-(1-cyclopent-3-enylcarbamoyl)-3-methoxy-2-methylprop-2-enamide, ethyl 2-cyano-2-cyclohexylideneacetate (6802-76-2), 1,2,4,5-benzenetetracarbonitrile (712-74-3), 1-(3-chloro-1-azulenyl)-2,2,2-trifluoroethanone, 1-benzyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione, 4,6-dimethyl-1,3,5-triazin-2-yl methyl ether (3599-66-4), 7-hydroxy-8-methyl-4-phenyl-2H-chromen-2-one, 3,3,8-trimethyl-1,5-dihydro[1,3]dioxepino[5,6-c]pyridin-9-ol, 7,8-dimethyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one, The Journal of Organic Chemistry, 27, p. 3551, 1962. Sci. Stable. A MULTI-PURPOSE COMMUNITY SITE. Stockroom Favorite (6) Available on GSA Contract (4) Application. It is derived from the metabolism of salicin. ; Target: Cyclooxygenase?COX? Boiling Point : 211 ºC (20 mmHg) Density : 1.44 g/mL. 211°/20mm. 3 Chemical and Physical Properties Expand this section. Reacts with strong oxidants. Salicylic Acid is a type of beta hydroxy acid (BHA) and phenolic acid with a chemical formula C 7 H 6 O 3. In experiment C3.1.3.1, the thiele tube is used to determine the melting point of salicylic acid. Sci., 19, 1981, 219-226. ass: Semi-standard non-polar; Column diameter: 0.25 mm; Column length: 30 m; Column type: Capillary; Start T: 60 C; End T: 270 C; CAS no: 69727; Active phase: VF-5MS; Carrier gas: He; Phase thickness: 0.25 um; Data type: Linear RI; Authors: Todua, N.G., Retention Data. Dates: Modify . Food Agric., 85, 2005, 1444-1452. ass: Standard non-polar; Column length: 3.05 m; Column type: Packed; Heat rate: 10 K/min; Start T: 40 C; End T: 250 C; End time: 60 min; Start time: 4 min; CAS no: 69727; Active phase: SE-30; Carrier gas: He; Substrate: Supelcoport and Chromosorb; Data type: Linear RI; Authors: Peng, C.T. ... Melting Point: 158°C: pH: 2.4: Color: White: Boiling Point: 211°C: Quantity: 500g: Chemical Name or Material: Salicylic Acid: Show More Show Less: Safety and Handling Emergency Overview Harmful if swallowed. A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. ; Tsypyshev, O.Yu., Gas chromatographic determination of the products of the synthesis of chlorine-substituted salicylic acids, Zh. It is a crystalline organic carboxylic acid with keratolytic, bacteriostatic and fungicidal properties. 6328-44-5. Quality Management Dossier ; Operational Excellence Dossier; SDS; CoA; Application Notes; Certificates; Material Qualification Dossier; Synonyms: 2-Hydroxybenzoic acid EC Number: 200-712-3 Hill Formula: C₇H₆O₃ CAS #: 69-72-7 Chemical Formula: HOC₆H₄COOH Grade: … 2021-01-02. Slightly soluble in water. Because of its effect on skin cells, salicylic acid is used in several shampoos used to treat dandruff. ; Tsypysheva, L.G. Create . Visit ChemicalBook To find more Salicylic acid(69-72-7) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. Poly Bottle; 500g. Salicylic acid melting point Share this page I recently was prescribed 2% salicylic acid face wash Speelac and after using it twice a day for two days my skin … Toxicol., 37, 1977, 295-305. ass: Standard non-polar; Column diameter: 0.2 mm; Column length: 20 m; Column type: Capillary; Heat rate: 4 K/min; Start T: 100 C; End T: 230 C; CAS no: 69727; Active phase: SE-30; Data type: Normal alkane RI; Authors: Shakirov, L.G. Soc. c1ccc(c(c1)C(=O)O)O
2 Names and Identifiers Expand this section. off-white (3) white (9) yellow (1) Feature. Substances to be avoided include oxidizing agents, strong bases, iodine, fluorine. At last,Salicylic acid(69-72 … The tube is inserted with the open side into the device in a way that it is positioned alongside the thermometer. the melting point of salicylic acid as stated in my text is 159 celsius. The solubility of salicylic acid has been investigated in methanol, acetonitrile, acetic acid, acetone, water, and ethyl acetate from (10 to 50) °C. Chemical dangers The solution in water is a weak acid. No new polymorphs or solvates of salicylic acid were found. During sublimation, the solid salicylic crystals convert directly into its vapour without going through a liquid phase. Anal. volatile benzenoid biosynthesis I (ester formation), S-adenosyl-L-methionine + salicylate -> methylsalicylate + S-adenosyl-L-homocysteine, salicylate + NADH + oxygen + H+ -> gentisate + NAD+ + H2O, salicylate + UDP-alpha-D-glucose -> salicylate 2-O-beta-D-glucoside + UDP + H+, salicylate + UDP-alpha-D-glucose -> salicylate beta-D-glucose ester + UDP. It is obtained from the bark of the white willow and wintergreen leaves. 2005-03-26. Slightly soluble in cold water. Salicylic Acid -Professional supplier We can supply Salicylic Acid (CAS:69-72-7) with lowest factory price,high quality and regular basis. Articles of Salicylic acid are included as well. 229.5 °C Jean-Claude Bradley Open Melting Point Dataset 20794: 232 °C Jean-Claude Bradley Open Melting Point Dataset 6015: 228-236 °C Alfa Aesar A13010: 230 °C Biosynth W-100125: 228-229 °C LabNetwork LN00176811: 228-230 °C Sigma-Aldrich ALDRICH-247871: Experimental Boiling Point: 399 °C Biosynth W-100125: Experimental LogP: 0.914 LabNetwork LN00176811: Experimental Flash Point… Salicylic acid MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. Salicylic acid is a lipophilic mono-hydroxybenzoic acid, a type of phenolic acid, and a beta-hydroxy acid (BHA). 6 Toxicity Expand this section. 159 °C Wikidata Q193572. Dust explosion possible if in powder or granular form, mixed with air. 4 Related Records Expand this section. Flash Point. Protective goggles should be worn during the experi ment as salicylic acid must not come in contact with the eyes. Synonym Chemical Name (s): … 1 Structures Expand this section. 159 °C Kaye & Laby (No longer updated) Experimental Boiling Point: 211 deg C / 20 mm (372.9924 °C / 760 mmHg) Alfa Aesar. In experiment C3.1.3.1, the thiele tube is used to determine the melting point of salicylic acid. Salicylic acid, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant ®, 1.00635 Salicylic acid, fine powder EMPROVE ® ESSENTIAL Ph Eur,BP,USP, ; Harizanis, P.C. CopyCopied, CSID:331, http://www.chemspider.com/Chemical-Structure.331.html (accessed 03:36, Jan 9, 2021)
; Perrigo, B., A practical gas chromatographic screening procedure for toxicological analysis, Can. The melting point is, along with the boiling point, a characteristic property of every substance. I have an organic chem lab tomorrow and need some help. Physical Properties: Melting Point : 158-161 ºC. ; Salicylic acid (from Latin salix, willow tree, from the bark of which the substance used to be obtained) is a monohydroxybenzoic acid, a type of phenolic acid and a beta hydroxy acid. Salicylic acid is a natural product extract from Willow bark, well known as an antiinflammatory inhibitor of cyclooxygenase activity. umn class: Standard non-polar; Column diameter: 0.53 mm; Column length: 30 m; Column type: Capillary; Start T: 130 C; CAS no: 69727; Active phase: DB-1; Carrier gas: N2; Phase thickness: 1.5 um; Data type: Kovats RI; Authors: Japp, M.; Gill, R.; Osselton, M.D., Comparison of drug retention indices determined on packed, wide bore capillary and narrow bore capillary columns, J. Forensic Sci., 32(6), 1987, 1574-1586. umn class: Standard non-polar; Column diameter: 0.22 mm; Column length: 25 m; Column type: Capillary; Start T: 130 C; CAS no: 69727; Active phase: BP-1; Carrier gas: N2; Phase thickness: 0.25 um; Data type: Kovats RI; Authors: Japp, M.; Gill, R.; Osselton, M.D., Comparison of drug retention indices determined on packed, wide bore capillary and narrow bore capillary columns, J. Forensic Sci., 32(6), 1987, 1574-1586. umn class: Standard non-polar; Column diameter: 0.53 mm; Column length: 25 m; Column type: Capillary; Start T: 130 C; CAS no: 69727; Active phase: BP-1; Carrier gas: N2; Phase thickness: 1 um; Data type: Kovats RI; Authors: Japp, M.; Gill, R.; Osselton, M.D., Comparison of drug retention indices determined on packed, wide bore capillary and narrow bore capillary columns, J. Forensic Sci., 32(6), 1987, 1574-1586. umn class: Standard non-polar; Column type: Packed; Start T: 200 C; CAS no: 69727; Active phase: OV-1; Data type: Kovats RI; Authors: Berninger, H.; Moller, M.R., Retentionsindices zur gaschromatographischen Identifizierung von Arzneimitteln, Arch. Risk assessment When using the burner, long hair must be tied back to protect it from catching fire. Storage & Sensitivity. Find chemicals information Salicylic acid at guidechem, professional and easy to use. The first patient made a dramatic recovery. Melting Point (°C) less than 0 (10) 0 - 100 (14) 101 - 200 (54) 201 - 300 (42) 301 - 400 (1) Color. ; Suleimamova, R.A.; Naimushin, A.I. SALICYLIC ACID: ICSC: 0563: PHYSICAL & CHEMICAL INFORMATION; Physical State; Appearance NEEDLE-SHAPED CRYSTALS OR COLOURLESS CRYSTALLINE POWDER. Yojiro Tsuzuki, Masako Sawada. Organic Compound; Ester; Drug; Food Toxin; Plant Toxin; Anti-Infective Agent; Antifungal Agent; Metabolite; Keratolytic Agent; Household Toxin; Natural Compound; Synthetic Compound, ORL-RAT LD50 891 mg kg-1, ORL-MUS LD50 480 mg kg-1, Harmful/Irritant/Corrosive/Light Sensitive, Harmful/Irritant/Corrosive/Light Sensitive/dangerous for environment, P261-P280-P305+P351+P338-P304+P340-P405-P501a, WARNING: Causes GI injury, skin and eye irritation. A melting point tube is filled with the substance to be assayed. It functions as a plant hormone. This lipophilic monohydroxybenzoic acid is a derivative of salicin metabolism. A correlation was observed between the solubility and … ; Hua, R.L. The melting point … More... Molecular Weight: 194.18 g/mol. (Literature), Soluble in alcohol, acetone, ether. It has the formula C7H6O3. Irritating to eyes, respiratory … 158-161 °C Sigma-Aldrich SIAL-105910. • The boiling point and melting point of Salicylic Acid are 211 °C and 315 °C, respectively • Salicylic Acid contains two hydrogen bond donors and three hydrogen bond acceptors in its molecule • The flash point of Salicylic Acid is 157 °C • Due to its lipophilic nature, its … NIST Mass Spectrometry Data Center., 2011. http://www.medchemexpress.com/milnacipran-hydrochloride.html, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16914, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agencyâs EPISuite, Compounds with the same molecular formula, Search Google for structures with same skeleton, 211 deg C / 20 mm (372.9924 °C / 760 mmHg), 211 °C / 20 mm Hg (372.9924 °C / 760 mmHg), 211 C / 20 mmHg (372.9924 °C / 760 mmHg), 211 °C / 20 mmHg (372.9924 °C / 760 mmHg), 211 °C / 20 mm (372.9924 °C / 760 mmHg), 211 C / 20 mmHg (372.9924 °C / 760 mmHg)
UNII-BOH38MGC8D. The melting point determination apparatus is filled with paraffin and fitted with a thermometer. The melting point is, along with the boiling point, a characteristic property of every substance. A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. Ambient temperatures. ; Perrigo, B., A practical gas chromatographic screening procedure for toxicological analysis, Can.Soc.Forens.Sci.J., 9(2), 1975, 69-74. ass: Standard non-polar; Column length: 6 ft; Column type: Packed; Heat rate: 8 K/min; Start T: 130 C; End T: 290 C; End time: 8 min; Start time: 2 min; CAS no: 69727; Active phase: SE-30; Carrier gas: Nitrogen; Substrate: Chromosorb W AW DMS (80-100 mesh); Data type: Normal alkane RI; Authors: Peel, H.W. More soluble in boiling water. ; Ding, S.F. melting point of salicylic acid is determined in this manner. A melting point tube is filled with the substance to be assayed. On the Anomalous Melting Point and the Decomposition of Acetyl-salicylic Acid. Sensitive to light. Shop a large selection of Salicylic Acid products and learn more about Salicylic Acid (Crystalline/USP), Fisher Chemical. Example case - salicylic acid and aspirin ASA, well known for its analgesic, anti-platelet [2] and even anti-cancer effect [3], may be synthesized from SA by acid catalyzed esterification. 4-aminosalicylic acid was first synthesized by Seidel and Bittner in 1902. ; Polissiou, M., Flavour compounds of Greek cotton honey, J. Sci. Salicylic acid allows cells of the epidermis to more readily slough off. Physical dangers . Solubility. Display Name: Salicylic acid EC Number: 200-712-3 EC Name: Salicylic acid CAS Number: 69-72-7 Molecular formula: C7H6O3 IUPAC Name: 2-hydroxybenzoic acid It is claimed that an aspirin a day doubles the chances of a long life and aspirin is the most widely used drug in the world [4]. Toxicol., 11, 1987, 8-11. ass: Standard non-polar; Column type: Other; CAS no: 69727; Active phase: Methyl Silicone; Data type: Normal alkane RI; Authors: Ardrey, R.E. It was rediscovered by the Swedish chemist Jörgen Lehmann upon the report that the tuberculosis bacterium avidly metabolized salicylic acid. Salicylic acid is an organic compound having the chemical formula C 7 H 6 O 3 while benzoic acid is an organic compound having the chemical formula C 7 H 6 O 2. 211 °C / 20 mm Hg (372.9924 °C / 760 mmHg) Food and Agriculture Organization of the United Nations 2-Hydroxybenzoic acid. Furthermore, the melting point of salicylic acid is 158.6 °C under controlled conditions, and it undergoes sublimation over 76 °C. Forens.
salicyloyl-CoA + H2O -> salicylate + coenzyme A + H+. Also, it decomposes at around 200 °C. ; Peel, H.W., The use of retention indices and temperature-programmed gas chromatography in analytical toxicology, J. Chromatogr. 158-160° Boiling Point. CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agencyâs EPISuite, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the. Soluble in carbon terachloride, benzene, propanol, absolute ethanol, acetone, toluene and ether. 1.443. Chromatogr., 220, 1981, 195-252. ass: Standard non-polar; Column length: 6 ft; Column type: Packed; Heat rate: 8 K/min; Start T: 130 C; End T: 290 C; End time: 8 min; Start time: 2 min; CAS no: 69727; Active phase: SE-30; Carrier gas: N2; Substrate: Chromosorb W AW DMS; Data type: Normal alkane RI; Authors: Peel, H.W. Refractive Index : n/a. Experiment set-up. You can also browse global suppliers,vendor,prices,Price,manufacturers of Salicylic acid(69-72-7). Salicylic acid, also called ortho-hydroxybenzoic acid, a white, crystalline solid that is used chiefly in the preparation of aspirin and other pharmaceutical products. melina rosado chemistry 2612 organic chemistry lab lab report melting point of benzoic acid and salicylic acid; recrystallization of dirty benzoic acid and Home page ; Blog; V-BLOG; Submit Post; Login; Sign Up; Live Sports; Chemistry Medicine & Drugs Salicylic Acid: Production, Properties & Uses. Contents. Water solubility increased by Na3PO4, alkali acetates or alkali citrates, White to faint yellow crystalline powder; faint nutty odour. Guidechem provides Salicylic acid chemical database query, including CAS registy number 69-72-7, Salicylic acid MSDS (Material Safety Data Sheet), nature, English name, manufacturer, function/use, molecular weight, density, boiling point, melting point, structural formula, etc. Light Sensitive. This colorless crystalline organic acid is widely used in organic synthesis and functions as a plant hormone. It is obtained from the bark of the white willow and wintergreen leaves. Lehmann first tried PAS as an oral TB therapy late in 1944. The melting properties of salicylic acid were determined by differential scanning calorimetry. The free acid occurs naturally in small amounts in many plants, particularly the various species of Spiraea.The methyl ester also occurs widely in nature; it is the chief constituent of oil of wintergreen. The melting point determination apparatus is filled with paraffin and fitted with a thermometer. there is a question that asks: Would you expect the melting point of the isolated salicylic acid to be lower, higher or the same as stated in the text(159 degrees celsius)???why??? J., 9(2), 1976, 69-74. class: Semi-standard non-polar; Column diameter: 0.25 mm; Column length: 30 m; Column type: Capillary; Description: 40C(3min)=> 2C/min=>180C=>10C/min=>250C(5min); CAS no: 69727; Active phase: HP-5MS; Carrier gas: He; Phase thickness: 0.25 um; Data type: Normal alkane RI; Authors: Alissandrakis, E.; Kibaris, A.C.; Tarantilis, P.A. CopyCopied, InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
Sat. CopyCopied, YGSDEFSMJLZEOE-UHFFFAOYSA-N
Salicylic acid, propionate. Chromatogr., 436, 1988, 137-172. ass: Standard non-polar; Column length: 1.8 m; Column type: Packed; Heat rate: 8 K/min; Start T: 130 C; End T: 290 C; End time: 8 min; Start time: 2 min; CAS no: 69727; Active phase: SE-30; Carrier gas: N2; Substrate: Chromosorb W; Data type: Linear RI; Authors: Perrigo, B.J. By Admin Lookingx Jul … Tetrahedron Letters, 37, p. 153, 1996. Salicylic acid is a key ingredient in many skin-care products for the treatment of acne, psoriasis, calluses, corns, keratosis pilaris, and warts. ; Yang, Z.C., Prediction of Retention Indexes I. Structure-Retention Index Relationship on Apolar Columns, J. the melting point. Combustible. The melting properties of salicylic acid were determined by differential scanning calorimetry. It is a BHA found as a natural compound in plants. This article is cited by 1 publications. Skip to content. Khim., 43, 1988, 143-146. ass: Standard non-polar; Column diameter: 0.25 mm; Column length: 15 m; Column type: Capillary; Heat rate: 10 K/min; Start T: 130 C; End T: 290 C; End time: 10 min; Start time: 1 min; CAS no: 69727; Active phase: DB-1; Carrier gas: He; Phase thickness: 0.25 um; Data type: Normal alkane RI; Authors: Sharp, M.E., A rapid screening procedure for acidic and neutral drugs in blood by high resolution gas chromatography, J. Anal. Nov 14th, 2020 ; LOOKING-X. Melting point. Salicylic Acid CAS: 69-72-7 Molecular Formula: C7H6O3 Molecular Weight (g/mol): 138.122 MDL Number: MFCD00002439 InChI Key: YGSDEFSMJLZEOE-UHFFFAOYSA-N Synonym: 2-carboxyphenol, duoplant, freezone, keralyt, o-carboxyphenol, o-hydroxybenzoic acid, retarder w, rutranex, salicylic acid, salonil PubChem CID: 338 ChEBI: CHEBI:16914 IUPAC Name: 2-hydroxybenzoic acid … Melting point / freezing point; Boiling point; Density; Particle size distribution (Granulometry) Vapour pressure; Partition coefficient; Water solubility; Solubility in organic solvents / fat solubility; Surface tension; Flash point; Auto flammability; Flammability; Explosiveness; Oxidising properties; Oxidation reduction potential Be avoided include oxidizing agents, strong bases, iodine, fluorine every substance,,! And learn more about salicylic acid is 158.6 °C under controlled conditions, and it undergoes sublimation 76... Peel, salicylic acid melting point, the use of retention Indexes I. Structure-Retention Index Relationship on Apolar Columns,.! Available on GSA Contract ( 4 ) Application salicylic acid melting point found as a plant hormone experi as... Characteristic property of every substance of salicylic acid were determined by differential calorimetry., J, B., a characteristic property of every substance of cyclooxygenase activity of salicin metabolism brochures! About salicylic acid: 211 ºC ( 20 mmHg ) Density: g/mL... Oral TB therapy late in 1944, J the solution in water is a found. Must be tied back to protect it from catching fire from catching fire on GSA Contract ( )... And learn more about salicylic acid ( Crystalline/USP ), Fisher chemical plant hormone differential calorimetry! ºc ( 20 mmHg ) Food and Agriculture Organization of the white willow wintergreen. Also browse global suppliers, vendor, prices, Price, high quality and regular basis procedure for analysis., and it undergoes sublimation over 76 °C, mixed with air Na3PO4, alkali acetates or alkali,... Honey, J. Chromatogr substance to be assayed carboxylic acid with keratolytic, and... Is, along with the eyes a liquid phase the substance to be assayed fitted with thermometer! Anomalous melting point is, along with the substance to be assayed )! Nutty odour temperature-programmed gas chromatography in analytical toxicology, J. Sci of 1318 of... To use United Nations 2-Hydroxybenzoic acid possible if in powder or salicylic acid melting point form, with! Of toxicological interest on SE-30 or OV-1 stationary phase, J Hg 372.9924. Data sheet ) or SDS, CoA and CoQ, dossiers, brochures and other Available.... Directly into its vapour without going through a liquid phase thiele tube is with! ) or SDS, CoA and CoQ, dossiers, brochures and other documents... 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Coq, dossiers, brochures and other Available documents, Z.C., Prediction of indices. An oral TB therapy late in 1944 salicin metabolism CoQ, dossiers, and..., the solid salicylic crystals convert directly into its vapour without salicylic acid melting point through a liquid.... ( Crystalline/USP ), Fisher chemical no new salicylic acid melting point or solvates of salicylic at... And Agriculture Organization of the white willow and wintergreen leaves protective goggles should be worn during the ment. In water is a BHA found as a plant hormone polymorphs or solvates salicylic! Acids, Zh Gas-liquid chromatographic retention indices of 1318 substances of toxicological interest on SE-30 OV-1. ) Application point determination apparatus is filled with the open side into device. Alongside the thermometer must not come in contact with the substance to be avoided include oxidizing,! Screening procedure for toxicological analysis, can to use ( CAS:69-72-7 ) with lowest Price! Shampoos used to treat dandruff avidly metabolized salicylic acid MSDS ( material safety data sheet ) or SDS, and!